BACKGROUND: Dystrophic calcinosis cutis is a common manifestation in connective tissue diseases, but there’s still no consensus on treatment. OBJECTIVES. Abstract. Objectives: To evaluate the effect of minocycline as treatment for cutaneous . Calcinosis cutis circumscripta: treatment with intralesional corticosteroid. An year-old woman was followed up for a year history of limited cutaneous systemic sclerosis complicated by recurrent subcutaneous lesions of calcinosis.

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A study reported that a low dose of the antibiotic minocycline was effective in relieving the pain and yreatment of lesions in people with CREST syndrome.

Recurrence is common after excision. The signs and symptoms of calcinosis cutis vary according to the underlying cause.

Radiological examinations including plain film x-ray, CT scanning and bone scintigraphy are useful in demonstrating the extent of tissue calcification. A solitary lesion may develop, although multiple lesions are more common. Self-skin examination New smartphone apps to check your skin Learn more Sponsored content.

Medications that may be tried include corticosteroids, probenecid, colchicine, sodium etidronate, diphosphonates, diltiazem, and magnesium and aluminium antacids. In general, tissue damage calcinosls to phosphate proteins released by dying cells which then calcify, forming calcium salts. The lesions may have no symptoms, or they may be severe, painful, or oozing a whitish substance. Causes of treatmenr cutis. If you have any concerns with your skin or its treatment, see a dermatologist for advice.


Hypercalcemia is a condition in which you have too much calcium in your blood. Conditions that can cause dystrophic calcinosis cutis include:. Laboratory tests are performed to determine any metabolic abnormalities that may give rise to elevated calcium and phosphate levels.

Because surgical trauma may stimulate further calcificationit may be best to excise a small site before going ahead with a large excision. Causes of the abnormal levels of calcium and phosphate are:. Normal serum calcium and phosphate levels exist. If your lesions are painful, get infected often, or impair your functioning, your doctor may recommend surgery.

Your doctor will examine you and take your medical history and ask you questions about your symptoms. Unlike the first two types of calcinosis cutis, idiopathic calcification occurs with no underlying tissue damage and no abnormal levels of calcium or phosphorus.

Pharmacological treatment in calcinosis cutis associated with connective-tissue diseases.

Diagnosis of calcinosis cutis. But in some cases, it can be very painful. Your Questions Answered Infrared saunas promise a number of health benefits, from weight loss and decreased stress levels to improved circulation ca,cinosis even better skin. The tissue damage can come from:.

For larger lesions, drugs that may help include:. Iatrogenic calcinosis cutis arises secondary to a treatment or procedure, for example parenteral administration of calcium or phosphate, and calcium deposition in newborns from repeated heel sticks. The doctor will likely order several laboratory tests to determine the underlying cause of your calcinosis cutis:. The appearance and location of calcinosis cutis depend on the underlying cause.


Calcinosis cutis | DermNet NZ

From worsening anxiety to making depression more likely, sugar is seriously harmful to your mental health. A new technology under development to aid diagnosis is advanced vibrational spectroscopy. Calcification Calcification occurs when calcium builds up in areas of body tissue where calcium normally doesn’t exist.

Breast calcifications, and identified by a mammogram and may indicate breast cancer. The lesions usually appear around fingers and elbows and may break open and leak a thick white material. In rare cases, a lesion may become life-threatening.

Outlook for calcinosis cutis.

Pharmacological treatment in calcinosis cutis associated with connective-tissue diseases.

What makes a carb good and what makes it bad? An estimated 25 to 40 percent of those with CREST syndrome will develop calcinosis cutis after 10 years. Biopsy of cutaneous lesions is used to confirm diagnosis. Lesions may become tender and ulcerate, discharging chalk-like creamy material consisting mainly of calcium phosphate with a small amount of calcium carbonate.

Conditions that can cause metastatic calcinosis cutis include:.